Trivellin, Giampaolo et al. Endocrine-Related Cancer. 2016 Mar
Giampaola Trivellin and colleagues investigate the orphan G protein-coupled receptor (GPR101) for its possible involvement in corticotropinomas. They performed a set of analyses in children with sporadic Cushing Disease (CD) and revealed a rare germline heterozygous GPR101 variant (p.G31S) in one patient with CD by sequencing analyses but their in vitro studies did not support a consistent pathogenic effect
"We were early Alamut adopters and this software has become essential to our daily diagnosis lab practice, saving time and reducing mistakes. The intuitivity of use and the new functionalities are a very useful help in our daily work."
PASCALE RICHARD M.D. Ph.D.
Paris, France
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