Patricia Moya and Juliana Salazar and colleagues present a study to evaluate whether polymorphisms in pharmacokinetic genes are associated with outcome in rheumatoid arthritis patients receiving Methotrexate (MTX). They showed that FPGS and ABCB1 genetic variants can influence the outcome in rheumatoid arthritis patients receiving MTX monotherapy.
Moya, Patricia et al. Pharmacogenomics.
"I have previously used Alamut Visual in the UK and it is an invaluable resource for variant curation which I was keen to bring into use in my new role in New Zealand. provides a convenient and user-friendly interface which pulls together literature searches, population databases and in silico prediction tools. This enables streamlining of the curation process and saves a lot of time."
Wellington Regional Genetics Laboratory, Wellington, New Zealand