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Voer, Richarda M. de et al. PLOS Genet.

Voer, Richarda M. de et al. PLOS Genet. 2016 Feb

Richarda Voer and colleagues report a study on novel candidate genes for colorectal cancer (CRC) at an early age in life. They applied a strategy for seraching genes with multiple rare (minor allele frequency <0.001) variants in cases but not in controls with a potentially damaging effect. They identified LRP6  and  PTPN12  as novel candidate genes for CRC susceptibility.



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