Robbert DA Weren and colleagues perform genome-wide and targeted DNA copy number profiling and resequencing in early-onset and familial polyposis/colorectal cancer (CRC) patients. They show that deletions affecting the open reading frame of the tumour suppressor gene FOCAD are recurrent and significantly enriched in CRC patients compared with unaffected controls.
Weren, Robbert DA et al. The Journal of Pathology.
"I recommend Alamut to all of my colleagues and friends in genomics!"
EDGARDO R. PARRILLA, MD
Duke University, Durham, USA