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Sommen, Manou et al. Human Mutation.

Sommen, Manou et al. Human Mutation. 2016 Apr

Manou Sommen and colleagues report a study of a targeted resequencing panel for hearing loss was developed including 79 genes for nonsyndromic hearing loss (NSH)L and selected forms of syndromic hearing loss.They established a straightforward variant classification system to deal with the large number of variants encountered and showed that after GJB2, the most commonly mutated genes in a Western-European population are TMC1, MYO15A, and MYO7A .



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Wellington Regional Genetics Laboratory, Wellington, New Zealand